Biophysical Characterization of MTA Plus chitosan conjugate for biomedical applications an in vitro study

Abstract

ABSTRACT:- Objective: The aim of the study was to evaluate the conjugation of MTA plus (Mineral Trioxide Aggregate Plus) and chitosan using FTIR, XRD and study the surface morphology of the conjugate with AFM. Material and Methods: MTA Plus was mixed with acetylated chitosan and a conjugate was formed. This conjugate was analyzed by FTIR, XRD, and AFM to study its biophysical properties and surface structure. Results: The conjugate formed was very much similar in composition and chemical changes or dergradation were not significant. Conclusion: The conjugate formed can be alternate material in non-surgical and surgical appliactions with better properties. Clinical Significance: The Conjugate formed using Chitosan has shown promising results. Hence, this conjugate will be the next material of choice as root end filling material and for pulp capping. The properties of chitosan will be synergistic with the root end materials and helps in faster and better healing of lesions.