A study to evaluate the antifungal efficacy of nanographene oxide incorporated in maxillofacial prosthesis material – An in vitro study

Abstract

Introduction: Maxillofacial prosthesis made of medical grade silicone elastomers are routinely used to replace facial parts lost through diseases or trauma. The prosthesis needs to be biocompatible to enable wound healing and the restoration of healthy tissue; but the material also needs to be aesthetically acceptable to the patient. Hence this basic cell viability analysis was planned to evaluate antifungal efficacy of nanographene oxide incorporated in maxillofacial prosthesis material. Material and methods: Thirty wax samples of 6mm diameter and 1mm in thickness were made in a denture acrylisation flask. This flask was heated in the boiling water to dewaxing procedure, which removed the wax patterns from these 30 moulds Results: Silicon discs incorporated with graphene oxide showed antifungal activity against candida albicans whereas silicon discs that is the control group showed no activity Conclusion: Incorporation of Graphene oxide in the maxillofacial silicone material can reduce the fungal growth.